ANTITUMOR EFFICACY AND ANTI-INFLAMMATORY EFFICACY IN BALANCE-alpha
We are frequently asked by customers who are taking Balance-alpha:
“I can surely feel good effects after taking Balance-alpha for a certain period but I wonder why and would like to have scientific data which explains the mechanism.”
We have been thinking how to respond to such inquires for quite a long time and one day we happened to hear of a private research institution “Immunity Analysis Laboratory” which developed from an internal venture of Kyoto University. This laboratory tests, measures and evaluates the influence of food and medicine for biological immunity systems.
We shared some perceptions with the person in charge in the Laboratory and decided to test macrophage activation in mice in order to see whether Balance-alpha has an immunostimulating power.
The result is the following.
The above chart shows the alteration of macrophage immunity factor production amounts when Balance-alpha was added gradually to the water contains macrophage.
This chart indicates two facts.
- Balance-alpha does not have an effect to induce NO production ability
- Balance-alpha induces TNF‐alpha（tumor necrosis factor）
TNF‐alpha（tumor necrosis factor）is produced mainly from macrophage and lymphocytes and induces various mmunostimulating effects as a bio-defense factor creating directly a cytotoxic action in some kind of tumor-cell. It is presumed that Balance-alpha attacks the tumor cells controlling TNF -alpha production quantity of macrophage.
The above chart shows the alteration of TNF -alpha production quantity when Balance-alpha was added changing the density to the water contains macrophage and macrophage active substance LPS. As the density of Balance-alpha becomes deep, the TNF-alpha production quantity decreases. Since TNF -alpha is known as a immune agent which leads to inflammation, it is presumed that Balance-alpha put TNFF -alpha productivity on hold in certain conditions and relieves inflammation.
From the results of the above examinations Immune Analysis Laboratory presumes that Balance-alpha is a complex substance with various immunostimulating factors rather than a single component because it induces TNF-alpha production ability and also depresses TNF-alpha production.
We could confirm that Balance-alpha has a certain immunomodulating ability.
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